What is PRP?
PRP is prepared on site in the clinic from the patient’s own blood. It consists of concentrated platelets, a type of blood cell vital to clotting, along with growth factors in a small amount of plasma. Platelets naturally release growth factors, which are specialised proteins that control cell replication and growth.PRP use include both aesthetic and medical indications.
- Facial, neck and body skin rejuvenation
- Acne scarring
- Reduction in fine lines and wrinkles,
- Hair-loss (alopecia)/thinning
- Nerve injury
- Bone repair and regeneration
The Role of Platelet Growth Factors
Platelets store numerous growth factors and other important compounds involved in cellular regeneration. These include platelet-derived growth factor (PDGF), among others. All of these substances are involved in healing via anti-inflammatory mechanisms and cell division. Growth factors and other cell-regulating compounds are released when platelets are activated.
In PRP therapy, platelets are typically activated by calcium chloride or thrombin. However, collagen is a natural platelet activator.1 Therefore, it is possible that artificial activation could be eschewed in favor of permitting natural activation to occur after patient application.