What is PRP?

What is PRP?

PRP is prepared on site in the clinic from the patient’s own blood. It consists of concentrated platelets, a type of blood cell vital to clotting, along with growth factors in a small amount of plasma. Platelets naturally release growth factors, which are specialised proteins that control cell replication and growth.PRP use include both aesthetic and medical indications.

Aesthetic indications:

  • Facial, neck and body skin rejuvenation
  • Acne scarring
  • Reduction in fine lines and wrinkles,
  • Anti-aging
  • Hair-loss (alopecia)/thinning

Medical indications:

  • Nerve injury
  • Tendonitis
  • Oesteoarthritis
  • Bone repair and regeneration

The Role of Platelet Growth Factors

Platelets store numerous growth factors and other important compounds involved in cellular regeneration. These include platelet-derived growth factor (PDGF), among others. All of these substances are involved in healing via anti-inflammatory mechanisms and cell division. Growth factors and other cell-regulating compounds are released when platelets are activated.

Platelet Activation

In PRP therapy, platelets are typically activated by calcium chloride or thrombin. However, collagen is a natural platelet activator.1 Therefore, it is possible that artificial activation could be eschewed in favor of permitting natural activation to occur after patient application.

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